Uterine Cancer
Clomiphene citrate to induce ovulation may increase cancer risk
Published in OBGYN and Reproduction Week, May 23rd, 2005
"Clomiphene citrate, a selective estrogen receptor modulator, increases estradiol levels and consequently may increase risk of cancer of the uterine corpus," explained M.D. Althuis, of the U.S. National Cancer Institute, and colleagues.
They "conducted a retrospective cohort study of 8,431 U.S. women (145,876 woman-years) evaluated for infertility during 1965-1988. Through 1999, 39 uterine cancers were ascertained by questionnaire or cancer and death registries. Poisson regression estimated adjusted rate ratios."
Althuis and team said,...
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