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Enteric Neurons
Neural-crest-derived cells examined, location and phenotype in mouse gut shown
July 4th, 2005
A study from Australia has reported on the location and phenotype of proliferating neural-crest-derived cells in the developing mouse gut. "Neural crest cells that originate in the caudal hindbrain migrate into and along the developing gastrointestinal tract to form the enteric nervous system. While they are migrating, neural-crest-derived cells are also proliferating," wrote H.M. Young and colleagues, University of Melbourne. "Previous studies have shown that the expression of glial-derived neurotrophic factor (GDNF) and endothelin-3 is highest in the embryonic caecum, and that GDNF alone or in combination with endothelin-3 promotes the...
Source: OBGYN & Reproduction Week (2005-07-04)
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