OBGYN & Reproduction Week
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Hormone Replacement Therapy
Once- and twice-weekly matricial estradiol transdermal systems compared
July 4th, 2005
Researchers in France "[compared] the efficacy and tolerability of three transdermal systems (Estrapatch 40, Estrapatch 60, and Oesclim 50)." They conducted a multicenter, randomized, open, three parallel group study on 421 postmenopausal women presenting with at least 35 hot flushes in the week preceding inclusion and treated for 6 28-day cycles with either Estrapatch 40 (n=141) or Estrapatch 60 (n=140) once a week or Oesclim 50 (n=140) twice a week, associated to oral NETA (Millligynon 2x0.6 mg tablets daily) from day 15 to day 28. "Hot flushes, mastodynia, bleeding, local skin tolerability and adhesiveness were reported on daily cards. Endometrial...
Source: OBGYN & Reproduction Week (2005-07-04)
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