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Immunology
Plasmacytoid DC may have an immunogenic effect in setting of VLP vaccination
July 4th, 2005
Plasmacytoid DC may have an immunogenic effect in setting of VLP vaccination. "Human papillomavirus (HPV) virus-like particles (VLP) are being extensively tested as vaccines for the prevention of HPV-associated cervical cancer. Dendritic cells (DC) acquire and present antigens, initiating innate and adaptive immune responses," researchers in the United States reported in a recent issue of European Journal of Immunology. P. Lenz and colleagues, U.S. National Cancer Institute, Bethesda, explained, "It has been shown previously that DC of the myeloid lineage are capable of generating adaptive immune responses to HPVVLP in vitro. However, the...
Source: OBGYN & Reproduction Week (2005-07-04)
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