OBGYN & Reproduction Week
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Intrauterine Growth Restriction
Dexamethasone use in early pregnancy poses IUGR risk
July 4th, 2005
Dexamethasone use in early pregnancy is associated with increase risk of intrauterine growth restriction, a study in rat demonstrates. "Intrauterine growth restriction (IUGR) is a major cause of perinatal death and neonatal morbidity and mortality. There are numerous causes of IUGR. Glucocorticoid-induced IUGR is highly relevant because administration of synthetic glucocorticoids, principally dexamethasone, to women threatened by premature labor is widely used in clinical practice. Fetal growth is directly related to placental growth and development," wrote R. Ain and colleagues, University of Kansas. Ain's team "analyzed the effect of dexamethasone...
Source: OBGYN & Reproduction Week (2005-07-04)
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