OBGYN & Reproduction Week
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Adrenoceptors
Neocortical and visuo-spatial activities studied, effect of malnutrition shown
July 4th, 2005
According to recent research from Chile, mild prenatal protein malnutrition increases alpha(2C)-adrenoceptor density in the cerebral cortex during postnatal life and impairs neocortical long-term potentiation (LTP) and visuo-spatial performance. "Mild reduction in the protein content of the mother's diet from 25 to 8% casein, calorically compensated by carbohydrates, does not alter body and brain weights of rat pups at birth, but leads to significant enhancements in the concentration and release of cortical noradrenaline during early postnatal life. "Since central noradrenaline and some of its receptors are critically involved in LTP and memory...
Source: OBGYN & Reproduction Week (2005-07-04)
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