Apoptosis

Micromolar taxol induced cell necrosis in HeLa cells

Published in OBGYN and Reproduction Week, December 12th, 2005

Micromolar taxol could be administered to induce cell necrosis in human cervical carcinoma HeLa cells.

According to recent research published in the journal Cancer Chemotherapy and Pharmacology, "Although the mode of action of taxol, when used in nanomolar or micromolar concentrations during long periods, is extensively studied, there are few data available on taxol-mediated cytotoxicity when the drug is applied for a short time alone or in combination with hyperthermia.

"We studied the effect of taxol and hyperthermia on cell cycle kinetics, proliferation, and mode of cell death in human cervical carcinoma HeLa cells, following a scheme which...

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Source: OBGYN and Reproduction Week (2005-12-12)

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