Published in OBGYN and Reproduction Week, December 19th, 2005
Study 1: Deregulation of X-linked genes may create genetic instability, thereby promoting mammary gland tumorigenesis.
"While contribution of X chromosome in the susceptibility of prostate and ovarian cancer has been demonstrated, the role of X-linked genes in breast cancinogenesis is not clearly known. This study investigated and compared the X-linked gene expression profiles of MMTV-c-myc transgenic mammary tumor (MT) or MMTV-c-myc/MT-tgf-alpha double transgenic mouse mammary tumor (DT) to lactating mammary gland," scientists writing in the journal Breast Cancer...
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