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Endometriosis

Reports summarize endometriosis study results from University of Tokyo

Published in OBGYN and Reproduction Week, December 25th, 2006

Researchers detail in "FR 167653, a p38 mitogen-activated protein kinase inhibitor, suppresses the development of endometriosis in a murine model," new data in endometriosis. "In various cells including endometriotic cells, p38 mitogen-activated protein kinase (MAPK) plays essential roles for inflammation, an etiological factor for endometriosis. We evaluated the effect of FR 167653, a p38 MAPK inhibitor, on the development of endometriosis using a murine model," scientists in Tokyo, Japan report.

"As an endometriosis model, estradiol-treated ovariectomized BALB/c mice were injected intraperitoneally with endometrial fragments of the syngenic donor mice. The animals...

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