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Ovarian Cancer Therapy

New ovarian cancer therapy research has been reported by scientists at Oita University

Published in OBGYN and Reproduction Week, February 19th, 2007

New investigation results, "Apicidin, a novel histone deacetylase inhibitor, has profound anti-growth activity in human endometrial and ovarian cancer cells," are detailed in a study published in International Journal of Molecular Medicine. "Histone deacetylase inhibitors (HDACIs) can inhibit proliferation, induce cell cycle arrest and stimulate apoptosis of cancer cells. Our purpose was to investigate the antiproliferative effects of a novel HDACI, apicidin, on the Ishikawa endometrial cancer cell line, the SK-OV-3 ovarian cancer cell line and normal human endometrial epithelial cells," investigators in Oita, Japan report.

"Endometrial and ovarian cancer cells were...

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