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Human Papillomavirus Genetics

Studies by I. Sokolova and co-authors describe new findings in human papillomavirus genetics

Published in OBGYN and Reproduction Week, December 10th, 2007

Researchers detail in 'Chromosomal biomarkers for detection of human papillomavirus associated genomic instability in epithelial cells of cervical cytology specimens,' new data in human papillomavirus. "The goal of this study was to compare how accumulation of chromosomal aberrations in human papillomavirus (HPV)-infected cells correlates with the severity of cervical dysplastic lesions. We assessed the frequency of genomic alterations for 35 different loci in a pilot biopsy study and selected two loci (3q26 and 8q24) with the highest frequency of copy number gains found in high-grade dysplasia and cancer," scientists in the United States report.

"These probes were...

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