Menopause

Studies from B.G. Choi and co-researchers yield new data on menopause

Published in OBGYN and Reproduction Week, May 5th, 2008

According to a study from the United States, " Observational studies suggest a strong relationship between menopause and vascular calcification. Receptor activator of nuclear factor-kappa Beta ligand (RANKL) and osteoprotegerin (OPG) are critical regulators of bone remodelling and modulate vascular calcification."

"We assessed the hypothesis that ovariectomy increases vascular calcification via the OPG/RANKL axis. Materials and methods Age-matched sexually mature rabbits were randomized to ovariectomy (OVX, n = 12) or sham procedure (SHAM, n = 12). One month post-procedure, atherosclerosis was induced by 15 months 0.2%-cholesterol diet and endothelial balloon...

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Source: OBGYN and Reproduction Week (2008-05-05)

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