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Endometrial Cancer

Research from K. Garg and co-authors reveals new findings on endometrial cancer

Published in OBGYN and Reproduction Week, January 25th, 2010

"Endometrial carcinomas (ECs) in Young women (<= 40 y) are Usually managed conservatively in selected patients. Whether oophorectomy with total hysterectomy is mandated for patients failing hormonal therapy is controversial," scientists writing in the American Journal of Surgical Pathology report.

"Recognition Of features that might discourage conservative management and ovarian preservation are currently poorly characterized. We evaluated these patients for DNA mismatch repair (MMR) protein defects to assess whether the MMR status had an impact on therapeutic decision making. Seventy ECs in women of 40 years of age or younger (n = 70) were identified from...

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