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Cervical Intraepithelial Neoplasia

Studies from Indiana University have provided new information about cervical intraepithelial neoplasia

Published in OBGYN and Reproduction Week, April 19th, 2010

According to a study from the United States, "Standard surgical treatment for CIN may impair fertility generating a need for alternative treatment options. We tested the efficacy and toxicity of oral DIM in the treatment of CIN 2 or 3 lesions."

"with biopsy-proven cervical intraepithelial neoplasia (CIN) 2 or 3 scheduled for loop electrosurgical excision procedure (LEEP) were randomized 2:1 to receive diindolylmethane (DIM) (BioResponse-DIM ®, BioResponse, Boulder, CO) orally at approximately 2 mg/kg/day for 12 weeks or placebo (defatted rice bran, BioResponse). were evaluated every 3-4 months for I year. Analysis of data LIP to I year was assessed including Pap...

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