Obesity, Fitness & Wellness Week
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Adipose Tissue
Researchers from University of California publish findings in adipose tissue
December 30th, 2006
Scientists discuss in "Pref-1, a preadipocyte secreted factor that inhibits adipogenesis" new findings in adipose tissue. According to recent research from the United States, "Preadipocyte factor 1 (Pref-1) belongs to the Notch/Delta/Serrate family of epidermal growth factor-like repeat-containing proteins. Pref-1 is highly expressed in 3T3-L1 cells but is extinguished during adipocyte differentiation." "Pref-1 serves as an excellent marker for preadipocytes. Furthermore, Pref-1 is an inhibitor of adipogenesis. Constitutive expression of Pref-1 inhibits, whereas antisense Pref-1 enhances, 3T3-L1 adipocyte differentiation. We found that Pref-1 is synthesized as a...
Source: Obesity, Fitness & Wellness Week (2006-12-30)
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