Obesity, Fitness & Wellness Week
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Biochemistry
Progress toward drug screening with a cell–transistor biosensor
July 14th, 2007
To develop selective measurement techniques for diagnostics, drug research, and the detection of poisons, researchers would like to combine the high specificity of biochemical reactors with universal microelectronics. Now, researchers at the Max Planck Institute for Biochemistry in Martinsried/Munich have shown that such bioelectronic hybrid systems are no longer just a utopian vision. In the journal Angewandte Chemie, they describe the coupling of a receptor to a silicon chip by means of a cell–transistor interface. Many receptors are coupled to ion channels within cell membranes. When the corresponding ligand binds to its receptor, the channel is opened, allowing ions...
Source: Obesity, Fitness & Wellness Week (2007-07-14)
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