Obesity, Fitness & Wellness Week
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Cancer
New genetic marker characterizes aggressiveness of cancer cells
July 14th, 2007
Levels of a small non-coding RNA molecule called let-7 appear to define different stages of cancer better than some of the "classical" markers for tumor progression, researchers from the University of Chicago report in the Proceedings of the National Academy of Sciences. By suppressing genes that are active in the developing embryo, silenced just before birth, and re-activated years later in many advanced cancers, the let-7 family of "microRNAs"—tiny snippets of RNA that can put the brakes on expression of selected genes—appears to prevent human cancer cells from reasserting their prenatal capacity to divide rapidly, travel and spread. Since they...
Source: Obesity, Fitness & Wellness Week (2007-07-14)
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