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Obesity, Fitness & Wellness Week

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Cancer



Researchers have provided new information about a protein responsible for colorectal cancer and the target of a potential drug against this cancer.



July 14th, 2007

Called clusterin, this protein has been linked to the development of tumor cells and resistance to cancer therapy, but how it works is not well understood. Pending questions include how this protein is expressed in normal and cancer cells, how it helps cancer cells escape ionizing radiation and chemotherapy, and which patients will benefit from treatment with a drug targeting clusterin.

Claus Lindbjerg Andersen, Torben Falck Orntoft, and colleagues from from the Molecular Diagnostic Laboratory, Department of Clinical Biochemistry, Aarhus University Hospital, DK8200 Aarhus N, Denmark, discovered that clusterin is not expressed in normal cells, while in 25 percent of...


Source: Obesity, Fitness & Wellness Week (2007-07-14)

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