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Obesity, Fitness & Wellness Week

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Depression



Commonly prescribed antidepressants associated with lower bone density in older men and women



July 14th, 2007

The class of antidepressant medications known as selective serotonin reuptake inhibitors may be associated with an increased rate of bone loss in older men and women, according to two articles in the Archives of Internal Medicine, one of the JAMA/Archives journals.

Selective serotonin reuptake inhibitors (SSRIs) treat depression by inhibiting the protein that transports serotonin, a neurotransmitter involved in sleep and depression, according to background information in the articles. This protein has recently been discovered in bone as well, raising the possibility that SSRIs may affect bone density and the risk of fracture. SSRIs account for about 62 percent of...


Source: Obesity, Fitness & Wellness Week (2007-07-14)

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