Obesity, Fitness & Wellness Week
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Amyotrophic Lateral Sclerosis
UCLA, Italian chemists move closer to solving Lou Gehrig's disease mystery
July 14th, 2007
Chemists from UCLA and the University of Florence in Italy may have solved an important mystery about a protein that plays a key role in a particular form of amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease, a progressive, fatal neurodegenerative disorder that strikes without warning. Joan Selverstone Valentine, UCLA professor of chemistry and biochemistry, has studied the protein — copper-zinc superoxide dismutase — since the 1970s, long before it was implicated in ALS in 1993. Since the link was discovered, Valentine’s laboratory has made more than two dozen mutant, ALS-causing enzymes, most of which have only one wrong amino acid out of 153, to...
Source: Obesity, Fitness & Wellness Week (2007-07-14)
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