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Type 1 Diabetes

Advanced glycation endproducts correlate with diabetes complications

Published in Obesity and Diabetes Week, March 10th, 2003

Advanced glycation endproducts correlate with diabetes complications.

"We investigated whether serum levels of N-(carboxymethyl)lysine (CML), non-CML advanced glycation endproducts (AGEs), or pentosidine are associated with severity of diabetic microvascular complications in patients with type I diabetes," researchers in Japan reported.

"Serum levels of CML, non-CML AGE, and pentosidine were measured by an enzyme-linked immunosorbent assay in 38 males, and 47 females aged 31±8 years (mean±S.D.) with type 1 diabetes for 18.7±7.0 years," said J. Miura and colleagues, Tokyo Women's Medical University, School of Medicine.

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