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Exercise

Exercise increases skeletal muscle uncoupling protein-3 gene expression

Published in Obesity and Diabetes Week, March 31st, 2003

Acute endurance exercise increases skeletal muscle uncoupling protein-3 gene expression in untrained but not trained humans.

According to a study from the United States and England, "In rodents, acute exercise increases skeletal muscle uncoupling protein (UCP) gene expression and is associated with elevations in serum nonesterified fatty acids (NEFA). To test whether contractions increase UCP mRNA levels in humans, vastus lateralis biopsies were obtained 1 hour postexercise from untrained and trained subjects and analyzed for UCP-2 and UCP-3 long (LICP-3L ) and short (UCP-3S ) isoforms."

"The acute exercise bout (graded cycling...

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