Physiology

Weight loss lowers VLDL-TG secretion rate by making nonsystemic fatty acids less available

Published in Obesity and Diabetes Week, April 14th, 2003

In women with abdominal obesity, weight loss lowered VLDL-triglyceride secretion rates by making nonsystemic fatty acids less available, a small study showed.

B. Mittendorfer and colleagues at Washington University, St. Louis, Missouri, studied "the effects of obesity and weight loss on lipoprotein kinetics ... in six lean women [body mass index (BMI): 21 ± 1 kg/m²] and seven women with abdominal obesity (BMI: 36 ± 1 kg/m²)."

They quantified VLDL-triglyceride (TG) and apolipoprotein B-100 (apoB-100) secretion rates in the women before and after a 10% weight loss using "stable isotope tracer techniques, in...

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Source: Obesity and Diabetes Week (2003-04-14)

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