Published in Obesity and Diabetes Week, June 2nd, 2003
Luciano Rossetti and colleagues focused on the hypothalamus, a region of the brain that affects food intake. In experiments with mice, they examined how neurons in the hypothalamus respond to increased concentrations of long-chain fatty acids by decreasing glucose production in the liver and relying on fats - rather than carbohydrates - as a source of fuel. Their results were published in the June 2003 issue of Nature Medicine.
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