Diabetes Pathogenesis

Development of type 2 diabetes in Japanese patients studied

Published in Obesity and Diabetes Week, June 16th, 2003

Both impaired insulin secretion and insulin resistance are involved in the development of type 2 diabetes in Japanese subjects.

"To clarify whether pancreatic beta-cell function and/or insulin resistance contributes to development of glucose intolerance in Japanese subjects, we investigated 551 subjects who underwent a 75-g oral glucose tolerance test (OGTT)," investigators in Japan report.

"Subjects were divided into three groups: normal glucose tolerance (NGT, n=238), impaired glucose tolerance (IGT, n=211), and newly diagnosed type 2 diabetes mellitus (n=102)," wrote Masao Kanauchi and collaborators at Nara Medical University. "The diabetics were...

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Source: Obesity and Diabetes Week (2003-06-16)

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