Heart Disease Therapy
Breaker of glycation end product reduces diabetic myocardial damage
Published in Obesity and Diabetes Week, June 16th, 2003
According to recent research from Australia, "The formation of advanced glycation end products (AGEs) on extracellular matrix components leads to accelerated increases in collagen cross linking that contributes to myocardial stiffness in diabetes. This study determined the effect of the crosslink breaker, ALT-711 on diabetes-induced cardiac disease."
"Streptozotocin diabetes was induced in Sprague-Dawley rats for 32 weeks," stated Riccardo Candido and collaborators at the Baker Heart Research Institute and the University of Melbourne. "Treatment...
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