Weight Loss
Leptin overexpression may inhibit weight loss in severely obese patients
Published in Obesity and Diabetes Week, July 14th, 2003
According to recent research from Italy, "The effects of short-term (three weeks) integrated body weight reduction (BWR) program [including energy-restricted diet, aerobic and strength exercise (5 days/week), and nutritional education and psychological counseling] on plasma leptin levels and body composition were investigated in 54 morbidly obese patients (38 females/16 males; mean BMI±SE: 41.8±0.1 kg/m2, range 35-58 kg/m2; mean age: 29.8±1.0 yr, age range: 18-46 yr)."
"The BWR program induced a significant (p<0.001) weight loss...
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