Published in Obesity and Diabetes Week, August 4th, 2003
"Type 2 diabetes combines two mechanisms, peripheral insulin resistance and beta-cell defect. In this disease, insulin secretion is rather difficult to evaluate because the multiplicity of tests exploring different aspects of insulin secretion and the complex relationships between beta-cell function and either insulin resistance or plasma glucose level. In glucose tolerant populations at risk of diabetes, insulin secretion has been found heterogeneous with large inter-individual variations," investigators in France report.
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