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Type 2 Diabetes Therapy

Glipizide therapeutic system to prevent diabetes disrupts glucose homeostasis

Published in Obesity and Diabetes Week, August 4th, 2003

The glipizide therapeutic system disrupted glucose homeostasis in normal glucose-tolerant (NGT), first-degree relatives of African American patients with type 2 diabetes.

"We examined the long-term metabolic effects of a potent sulfonylurea (SU), glipizide gastrointestinal therapeutic system (glipizide GITS) in normal glucose-tolerant (NGT), first-degree relatives of African American patients with type 2 diabetes in a randomized, placebo-controlled, double-blind manner for 24 months and 6 months after discontinuation of glipizide GITS," researchers in the United States report.

"Fifty NGT African American first-degree relatives (n=50) were randomized...

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