Published in Obesity and Diabetes Week, September 15th, 2003
OEA, or oleylethanolamide, is known to regulate feelings of "fullness" and body weight. Daniele Piomelli and colleagues writing in the September 4, 2003, issue of Nature showed that the molecule binds to the nuclear protein, mimicking the action of other synthetic PPAR-alpha-stimulating drugs. It reduces weight gain in normal mice, but fails to do so in mice...
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