Cell Biology

Fibroblasts hold clues to fat, scars, and inflammation

Published in Obesity and Diabetes Week, October 13th, 2003

Scientists used to think that fibroblasts - the cells that form basic tissue structures - were little more than scaffolding on which more important cells would climb. But University of Rochester Medical Center researchers have discovered that certain fibroblasts have highly specialized duties and play a major role in how scars form, fat accumulates, and harmful inflammation arises in humans.

The research is published in the American Journal of Pathology, October 2003 edition. The work may help doctors understand why some people suffer from unexplained internal scarring around vital organs, which can lead to serious diseases of the eyes, lungs, heart, kidneys or...

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Source: Obesity and Diabetes Week (2003-10-13)

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