Published in Obesity and Diabetes Week, November 10th, 2003
According to a study from Spain, "In contrast to the consistent observation that methods that promote proliferation also dedifferentiate insulin-producing cells, useful in vitro differentiation protocols must drive both proliferation and differentiation."
"We herein describe an strategy in which the combination of nutrient restriction and nicotinamide supplementation results in a consistent increase in the mass of insulin-producing cells," wrote P. Vaca and colleagues at the University Miguel Hernandez.
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