Obesity & Diabetes Week
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Diabetes Pathogenesis
Free fatty acids contribute to impairment of insulin secretion
November 24th, 2003
Free fatty acids contribute to the impairment of insulin secretion and action. According to recent research published in the journal MS - Medecine Sciences, "Type 2 diabetes is characterized by two major defects: a dysregulation of pancreatic hormone secretion (quantitative and qualitative - early phase, pulsatility - decrease of insulin secretion, increase in glucagon secretion), and a decrease in insulin action on target tissues (insulin resistance). The defects in insulin action on target tissues are characterized by a decreased in muscle glucose uptake and by an increased hepatic glucose production." "These abnormalities are linked to...
Source: Obesity & Diabetes Week (2003-11-24)
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