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Diet and Nutrition
In vivo alpha-tocopherol effects offset by reduced gamma- and delta-tocopherol levels
November 24th, 2003
The benefits of alpha-tocopherol supplements are offset by its effects on levels of other tocopherols. "Despite promising evidence from in vitro experiments and observational studies, supplementation of diets with alpha-tocopherol has not reduced the risk of cardiovascular disease and cancer in most large-scale clinical trials," scientists in the United States explained. "One plausible explanation is that the potential health benefits of alpha-tocopherol supplements are offset by deleterious changes in the bioavailability and/or bioactivity of other nutrients." In a recent study, H.Y. Huang and colleagues at Johns Hopkins University evaluated "the...
Source: Obesity & Diabetes Week (2003-11-24)
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