Obesity & Diabetes Week
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Type 2 Diabetes Pathogenesis
Transmitted beta-cell dysfunction can cause type 2-diabetes
November 24th, 2003
Transmitted beta-cell dysfunction can cause type 2-diabetes. "The pathways that control insulin release and regulate pancreatic P-cell mass are crucial on the development of type 2 diabetes mellitus. Maturity-onset diabetes of the young comprises a number of single-gene disorders affecting P-cell development and/or function," a researcher in France reports. "A genetic basis for the more common forms of type 2 diabetes which affect adults in developed as well as many developing countries is less clear cut," said Bernard Portha at the University of Paris 7. "It is also characterized by abnormal P-cell function. Appropriate inbred rodent models are an...
Source: Obesity & Diabetes Week (2003-11-24)
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