Diabetes Therapy
Lagerstroemin activates insulin receptors
Published in Obesity and Diabetes Week, December 1st, 2003
"Lagerstroemin, an ellagitannin isolated from the leaves of Lagerstroemia speciosa (L.) Pers. (Lythraceae), was examined for its biological activities," scientists writing in the Journal of Pharmacological Sciences report.
"In rat adipocytes, the compound increased the rate of glucose uptake and decreased the isoproterenol-induced glycerol release," said Katsuji Hattori and colleagues at Hiroshima University. "In Chinese hamster ovary cells expressing human insulin receptors, it increased the Erk activity. These insulin-like actions were...
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