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Type 2 Diabetes Pathogenesis

Adipocytokins, obesity, and type 2 diabetes development reviewed

Published in Obesity and Diabetes Week, December 1st, 2003

The relations among adipocytokines, obesity, and the development of type 2 diabetes are examined in a review published in the French journal MS - Medecine Sciences.

"Normal metabolic balance is maintained by a complex homeostatic system involving multiple tissues and organs. Acquired or inherited defects associated to environmental factors in any part of this system can lead to metabolic disorders such as the syndrome X which is presently a frequent syndrome in industrialized countries. It is characterized by a cluster of risk factors of atherosclerosis including insulin resistance, hyperinsulinemia, impaired glucose tolerance or type 2 diabetes, hypertension,...

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