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Obesity Pathogenesis

Key genes related to obesity identified

Published in Obesity and Diabetes Week, December 8th, 2003

Obesity as a genetic disease is reviewed in a recent issue of the Journal of Internal Medicine.

According to researchers in the United States, "Obesity is one of the most pressing problems in the industrialized world. Twin, adoption, and family studies have shown that genetic factors play a significant role in the pathogenesis of obesity. Rare mutations in humans and model organisms have provided insights into the pathways involved in body weight regulation."

"Studies of candidate genes indicate that some of the genes involved in pathways regulating energy expenditure and food intake may play a role in the predisposition to obesity," said Ruth...

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