Hypertension
Human tissue kallikrein gene therapy reduces hypertension and hyperinsulinemia
Published in Obesity and Diabetes Week, December 22nd, 2003
According to recent research from the People's Republic of China, "this study investigates gene therapy with human tissue kallikrein as a treatment for fructose-induced hypertension in rats. Hypertension was induced by addition of 10% fructose to drinking water. Fructose-fed rats also had increased serum insulin and triglycerides, decreased urine osmolarity, increased urine volume and endothelin-1, and increased aortic endothelin-1, endothelin-A receptor, and angiotensin II receptor type 1 mRNA levels."
"Fructose-induced hypertensive and control rats were injected...
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