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Weight Gain

Rats gain weight over extended kindling of basolateral amygdala

Published in Obesity and Diabetes Week, December 22nd, 2003

Excessive weight gain in rats occurred over extended kindling of the basolateral amygdala.

According to recent research from Germany, "Previous lesion studies have indicated a role of the amygdala in the central regulation of food intake. In the present experiments, twice-daily electrical stimulation of the basolateral nucleus of the amygdala in female Wistar rats was found to be associated with a significant body weight gain compared to unstimulated controls."

"On average, significant increases in body weight were observed after 25 amygdala stimulations, using a kindling paradigm for stimulation," reported Wolfgang Loscher and colleagues at the...

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