Acute Pancreatitis
Lower HLA-DR on blood monocytes occurs prior to pancreatic organ failure
Published in Obesity and Diabetes Week, December 22nd, 2003
According to a study from Finland, "immune suppression plays an important role in the pathogenesis of acute pancreatitis. Monocyte expression of HLA (human leucocyte antigen)-DR, a cellular marker of immune suppression, was determined in relation to the development of organ dysfunction in patients with acute pancreatitis.
"A total of 310 consecutive patients with acute pancreatitis, admitted to a university hospital within 72 h of pain onset, were studied; 194 (63%) had mild disease (group 1), 87 (28%) had severe disease without organ dysfunction (group 2),...
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