Diabetes Genomics and Genetics

Gene linked to type 2 diabetes in population from the Netherlands

Published in Obesity and Diabetes Week, January 12th, 2004

A gene was linked to type 2 diabetes in a recently genetically isolated population from the Netherlands.

"Multiple genes, interacting with the environment, contribute to the susceptibility to type 2 diabetes. We performed a genome-wide search to localize type 2 diabetes susceptibility genes in a recently genetically isolated population in the Netherlands. We identified 79 nuclear families with type 2 diabetes who were related within 13 generations and performed a 770-marker genome-wide scan search for shared founder alleles," scientists in the Netherlands and U.K. report.

"Twenty-six markers yielded a logarithm of odds (LOD) score>0.59 (nominal...

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Source: Obesity and Diabetes Week (2004-01-12)

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