Insulin
Microfabricated needles used for transdermal delivery of insulin
Published in Obesity and Diabetes Week, January 26th, 2004
"Arrays of micrometer-scale needles could be used to deliver drugs, proteins, and particles across skin in a minimally invasive manner. We therefore developed microfabrication techniques for silicon, metal, and biodegradable polymer microneedle arrays having solid and hollow bores with tapered and beveled tips and feature sizes from 1 to 1,000 pm," scientists writing in the journal Proceedings of the National Academy of Sciences USA report.
"When solid microneedles were used, skin permeability was increased in vitro by orders of magnitude for...
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