Heart Disease Risk
Mitochondrial DNA variant linked to left ventricular hypertrophy in diabetes
Published in Obesity and Diabetes Week, February 2nd, 2004
"Diabetes was reported to be associated with a mitochondrial (mt) DNA mutation at 3,243 and variants at 1,310, 1,438, 3,290, 3,316, 3,394, 12,026, 15,927, and 16,189. Among these mtDNA abnormalities, those at 3,243, 3,316, 15,927, and 16,189 were also suggested to cause cardiomyopathies. We investigated the prevalence of such mtDNA abnormalities in 68 diabetic patients with LV hypertrophy (LVH), 100 without LVH, and 100 controls," scientists writing in the journal Biochemical and Biophysical Research Communications report.
"Among the 9 mtDNA abnormalities,...
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