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Diabetes Pathogenesis

Insulin resistance found in offspring of rats using alcohol while pregnant

Published in Obesity and Diabetes Week, February 9th, 2004

Insulin resistance developed in the offspring of rats that consumed alcohol while pregnant.

According to a study from Canada, "This study examined the effects of maternal ethanol (EtOH) consumption during pregnancy or lactation on glucose homeostasis in the adult rat offspring. Glucose disposal was determined by minimal model during an intravenous glucose tolerance test in rats that had a small or normal birth weight after EtOH exposure in utero and in rats whose mothers were given EtOH during lactation only. All three EtOH groups had decreased glucose tolerance index and insulin sensitivity index, but their glucose effectiveness was not different from that of...

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