Stem-Cell Research
Bone marrow-derived endothelial cells aid islet transplant survival
Published in Obesity and Diabetes Week, February 23rd, 2004
"Endothelial progenitor cells (EPCs) are detectable in the blood and bone marrow throughout life. These cells contribute to new blood vessel formation (neovascularization) in physiological states such as wound healing and in pathological states such as tumor angiogenesis. We hypothesized that bone marrow-derived EPCs could play a role in the response to pancreatic islet cell injury," investigators in the United States report.
"We used a murine model of experimentally induced beta-cell injury followed by transplantation with genetically marked bone marrow cells. Bone marrow-derived...
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