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Alzheimer Disease

Possible mechanism for link between diabetes and AD discovered

Published in Obesity and Diabetes Week, March 8th, 2004

For some time, researchers have known that people with diabetes have a greater risk of developing Alzheimer disease and other forms of dementia than those without diabetes, but the exact cause of this link has not been known.

Now, a new study by researchers in Cologne, Germany, and at Joslin Diabetes Center in Boston, published online the week of February 20, 2004, in the Proceedings of the National Academy of Sciences, suggests that insulin resistance in brain cells can affect how they function, causing some of the biochemical changes typically seen in Alzheimer disease.

Insulin resistance is a major contributor to type 2 diabetes, obesity...

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