Diabetes Genomics & Genetics

Tropomyosin-encoding gene expression depends on vasopressin gene

Published in Obesity and Diabetes Week, March 22nd, 2004

Expression of tropomyosin-encoding gene in the kidney depends on functioning of the vasopressin gene.

According to recent research from Russia, "Brattleboro diabetes insipidus mutant rats and normal WAG rats were subjected to water loading or thirst during three days. It was found that tropomyosin-encoding gene expression has a tissue-specific pattern in the kidney. Northern blot and western blot analysis had shown that the main expression of Tpm3³ takes place in the renal medulla, and its intensity differs in normal and mutant rats."

"The differences between mutants with an ineffective vasopressin synthesizing system and the rats having...

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Source: Obesity and Diabetes Week (2004-03-22)

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