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Postprandial suppression of ghrelin does not predict intermeal interval

Published in Obesity and Diabetes Week, April 19th, 2004

Postprandial suppression of plasma ghrelin level is proportional to ingested caloric load but does not predict intermeal interval in humans.

According to recent research published in the Journal of Clinical Endocrinology and Metabolism, "Plasma ghrelin levels rise before meals and fall rapidly afterward. If ghrelin is a physiological meal-initiation signal, then a large oral caloric load should suppress ghrelin levels more than a small caloric load, and the request for a subsequent meal should be predicted by recovery of the plasma ghrelin level."

"To test this hypothesis, 10 volunteers were given, at three separate sessions, liquid meals...

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