Published in Obesity and Diabetes Week, April 19th, 2004
The study examined four immunoassays and high performance liquid chromatography (HPLC), the method used by the U.S. Food and Drug Administration-cleared Accumin Direct Total Intact Albumin Assay (HPLC).
The results found variations in each methodology examined. The authors suggest that the Accumin HPLC method may provide a global standard, citing previous research indicating HPLC detects microalbuminuria in urine earlier than other commonly used albumin assays.
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